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GNX does not affect astrocytic activation in the vicinity of the demyelination lesion. A, Immunofluorescent staining image of the astrocytic marker GFAP. GNX did not affect the percentage area covered by GFAP (B) or average GFAP optical density (C) in the vicinity of demyelinated area of the corpus callosum of OVX rats when compared to those seen in vehicle‐treated OVX rats (Lyso‐Vehicle: n = 5, Lyso‐GNX: n = 4, P > .05). Scale bar = 50 µm
