Fig. 3.

Future directions for belatacept treatment in kidney transplant recipients. A more tailored approach in the selection, treatment strategy, and postconversion monitoring might be a way to expand the use of belatacept in kidney transplant recipients. AR acute kidney transplant rejection, CNI calcineurin inhibitors, DGF delayed graft function, DM diabetes mellitus, DSA donor-specific anti-HLA antibodies, EBV Epstein–Barr virus, HLA human leucocyte antigen, MPA mycophenolic acid, mTOR mammalian target of rapamycin, PD-1 programmed death-1, PRA panel reactive antigens, TAC tacrolimus, Th17 T helper 17, TMA thrombotic microangiopathy, Treg regulatory T cells