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. 2020 Jan 23;5:6. doi: 10.1038/s41541-020-0156-y

Fig. 1. F1/V vaccine increased protective levels of antibody, CD4+ T-cell, and IFN-γ responses.

Fig. 1

a Macrophage-protective levels of antibodies were statistically significantly increased from pre-vaccination on days 14 and 28 with highest response on day 28 post-second vaccination (Wilcoxon signed-rank test P-values are shown). b–d CD4+ that expressed IL-10, IL-4, or co-expressed TNF-α and IFN-γ were statistically increased from pre-vaccination on day 28 but not day 14. e IFN-γ cytokine concentrations measured in culture supernatants were statistically significantly increased from pre-vaccination on day 14 but not day 28. Statistical significance is based on Wilcoxon signed-rank test.