Table 2.
Multivariate logistic regression analysis to determine risk factors affecting CAC.
| Variables | All participants | Obese participants | Non-obese participants | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Age | 1.11 (1.10–1.12) | <0.001 | 1.12 (1.10–1.13) | <0.001 | 1.11 (1.10–1.12) | <0.001 |
| Male sex | 3.24 (2.65–3.97) | <0.001 | 3.59 (2.67–4.83) | <0.001 | 2.88 (2.16–3.83) | <0.001 |
| Hypertension | 1.82 (1.57–2.11) | <0.001 | 1.65 (1.34–2.03) | <0.001 | 2.06 (1.66–2.56) | <0.001 |
| Diabetes | 1.82 (1.43–2.33) | <0.001 | 1.70 (1.19–2.44) | 0.004 | 1.98 (1.42–2.77) | <0.001 |
| Obesity | 1.27 (1.08–1.49) | 0.004 | ||||
| Abdominal obesity | 1.12 (0.90–1.40) | 0.298 | 1.26 (0.71–2.26) | 0.428 | 1.19 (0.91–1.55) | 0.216 |
| NAFLD | 1.23 (1.06–1.44) | 0.007 | 1.20 (0.95–1.52) | 0.122 | 1.25 (1.02–1.54) | 0.034 |
| eGFR | 1.00 (0.99–1.01) | 0.836 | 1.01 (1.00–1.02) | 0.150 | 0.99 (0.99–1.00) | 0.091 |
| CRP | 1.00 (0.99–1.02) | 0.904 | 1.00 (0.98–1.01) | 0.905 | 1.01 (0.99–1.04) | 0.397 |
| Current smoking | 1.27 (1.07–1.51) | 0.008 | 1.14 (0.88–1.48) | 0.310 | 1.44 (1.13–1.84) | 0.004 |
| Alcohol status | 1.06 (0.90–1.24) | 0.517 | 1.18 (0.92–1.51) | 0.192 | 0.95 (0.77–1.19) | 0.678 |
| AST | 1.01 (1.00–1.02) | 0.006 | 1.02 (1.00–1.03) | 0.013 | 1.01 (1.00–1.02) | 0.049 |
| ALT | 1.00 (0.99–1.00) | 0.252 | 1.00 (1.00–1.00) | 0.482 | 0.99 (0.98–1.00) | 0.083 |
| γ-GT | 1.00 (1.00–1.00) | 0.077 | 1.00 (1.00–1.00) | 0.798 | 1.00 (1.00–1.01) | 0.027 |
CAC, coronary artery calcification; NAFLD, non-alcoholic fatty liver disease; eGFR, estimated glomerular filtration rate; CRP, C-reactive protein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; γ-GT, gamma-glutamyl transpeptidase; OR, odds ratio; CI, confidence interval.