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. 2020 Jan 23;11(1):53. doi: 10.1038/s41419-020-2237-2

Fig. 7. TSP-4 promotes accumulation of pro-inflammatory macrophages in peritoneal tissue of mice with LPS-induced peritonitis.

Fig. 7

a Expression of CD68, CD38, and Egr-2 was measured in peritoneal tissues of WT mice with LPS-induced peritonitis; n = 3; *p<0.05. b Expression of CD68 and CD38 was measured in peritoneal tissues of Thbs4−/− mice with LPS-induced peritonitis; n = 3; *p < 0.05. c Expression of CD68 and CD38 was measured in peritoneal tissues of P387-TSP-4-KI mice with LPS-induced peritonitis; n = 3; *p < 0.05. d Migration of RAW264.7 was measured in Boyden chambers (uncoated, coated with A387 or P387 rTSP-4, or BSA); n = 3; *p < 0.05 compared with plastic and BSA; #p < 0.05 compared with WT rTSP-4. e A387 and P387 rTSP-4 were used in adhesion competition assay: plastic was coated with P387 rTSP-4, and RAW264.7 was added in increasing concentrations; n = 3; *p < 0.05.