Table 4.
Multivariate analyses of prognostic factors for overall survival in young (age <60 years) MDS patients
| OS multivariate analysis | |||
|---|---|---|---|
| HRa | 95% CI | p value | |
| Sex | 1.664 | 0.398–6.954 | .485 |
| IPSS stratification | 4.181 | 1.908–9.159 | .000 |
| MIR‐378 hypomethylation | 6.619 | 1.694–25.864 | .007 |
| IDH1/2 mutation | 7.827 | 0.685–89.402 | .098 |
| DNMT3A mutation | 17.391 | 1.551–194.943 | .021 |
| U2AF1 mutation | 1.410 | 0.364–5.456 | .619 |
| SF3B1 mutation | 31.725 | 2.604–386.451 | .007 |
Abbreviations: CI, confidential interval; HR, hazard ratio; IPSS, International Prognostic Scoring System; MDS, myelodysplastic syndrome; OS, overall survival.
a
HR >1 indicates an increased risk of an event for the first category listed.