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. 2019 Sep 1;4(7):763–775. doi: 10.1016/j.jacbts.2019.07.011

Figure 3.

Figure 3

Markers of Platelet-Mediated Thrombogenicity

CAT-induced maximal platelet aggregation (MPA%) measured by light transmittance aggregometry (LTA). The p values represent comparisons between the 2 groups at each time point. Error bars indicate SD. The agonist CAT is a combination of collagen-related peptide, adenosine diphosphate, and thrombin receptor activating peptide. Intragroup comparisons for non-DM: Baseline versus DAPT + vorapaxar: mean difference = 20; 95% CI: 15 to 25; p < 0.001. Baseline versus clopidogrel + vorapaxar: mean difference = 10; 95% CI: 3 to 16; p < 0.001. DAPT + vorapaxar versus clopidogrel + vorapaxar: mean difference = 10; 95% CI: 4 to 16; p = 0.003. Intragroup comparisons for DM: Baseline versus DAPT + vorapaxar: mean difference = 15; 95% CI: 7 to 23; p < 0.001. Baseline versus clopidogrel + vorapaxar: mean difference = 3; 95% CI: −6 to 11; p = 0.542. DAPT + vorapaxar versus clopidogrel + vorapaxar: mean difference = 12; 95% CI: 3 to 21; p = 0.010. Abbreviations as in Figure 1.