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The effect of 100 μM 2dDR and VEGF on tube formation was assessed with Matrigel® tube formation assay. The quantified results of the average number of branch points and the number of tubes per field were given in the graphs given [****p ≤ 0.0001, **p ≤ 0.01, *p ≤ 0.05, not significant (ns) p ≥ 0.05, n = 3]. Scale bars represent 250 μm.
