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Differentiation process of adherent macrophages from suspension THP-1 induced by PMA stimulation (A). Release profile of IL-1β (B), TNF-α (C) and TGF-β1 (D) by macrophages derived from THP-1 after contact with PEG-PLA, PEG-PLGA, PEG-PLA-PEG aggregates, negative group and positive group. △ represented p > 0.05, * p < 0.05, ** p < 0.01, and *** p < 0.001 versus negative control.
