Table 5.
Least squares means (log2-back-transformed) for expression of genes in the liver, skeletal muscle, and subcutaneous adipose tissue of pigs fed diets containing 0 or 150 mg Cu/kg from copper hydroxychloride1
| Diet | ||||
|---|---|---|---|---|
| Item2 | Control | Control + Cu3 | SEM | P-value |
| Liver | ||||
| FAS | 0.681 | 0.926 | 0.192 | 0.329 |
| CD36 | 0.839 | 1.094 | 0.064 | 0.017 |
| ACC | 0.823 | 0.886 | 0.136 | 0.746 |
| PPAR-α | 0.857 | 0.923 | 0.089 | 0.451 |
| CPT1A | 1.031 | 1.000 | 0.078 | 0.678 |
| FABP1 | 0.774 | 1.137 | 0.098 | 0.067 |
| Skeletal muscle | ||||
| FAS | 0.678 | 1.314 | 0.315 | 0.742 |
| CD36 | 1.031 | 1.391 | 0.219 | 0.215 |
| ACC | 0.564 | 0.809 | 0.245 | 0.418 |
| PPAR-α | 0.732 | 0.877 | 0.046 | 0.082 |
| CPT1B | 0.877 | 0.835 | 0.077 | 0.682 |
| FABP3 | 0.889 | 0.797 | 0.062 | 0.308 |
| FATP1 | 0.826 | 0.687 | 0.069 | 0.158 |
| Subcutaneous adipose tissue | ||||
| FAS | 0.559 | 0.951 | 0.334 | 0.312 |
| CD36 | 1.031 | 1.391 | 0.219 | 0.215 |
| ACC | 0.564 | 0.809 | 0.245 | 0.418 |
| PPAR-α | 0.784 | 0.966 | 0.119 | 0.188 |
| CPT1B | 0.960 | 1.395 | 0.126 | 0.075 |
| FABP4 | 0.998 | 1.320 | 0.149 | 0.035 |
| FATP1 | 1.081 | 1.159 | 0.107 | 0.651 |
| PPAR-ɤ | 1.049 | 1.396 | 0.182 | 0.160 |
| LPL | 0.985 | 1.462 | 0.143 | 0.004 |
| HSL | 0.802 | 1.135 | 0.184 | 0.126 |
1Data are least squares means of seven or eight observations for all treatments.
2 FAS, fatty acid synthase; CD36, cluster of differentiation 36/fatty acid translocase; ACC, acetyl CoA carboxylase; PPAR-α, peroxisome proliferator-activated receptor alpha; CPT1A, carnitine palmitoyl transferase 1 A; FABP1, fatty acid binding protein 1; CPT1B, carnitine palmitoyl transferase 1 B; FATP1, fatty acid transport protein 1; FABP3, fatty acid binding protein 3; FABP4, fatty acid binding protein 4; PPAR-γ, peroxisome proliferator-activated receptor γ; LPL, lipoprotein lipase; HSL, hormone sensitive lipase.
3The diet containing added Cu was fortified with 150 mg/kg of Cu from copper hydroxychloride (IntelliBond CII; Micronutrients USA; Indianapolis, IN).