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. 2019 Dec 11;39(50):10071–10080. doi: 10.1523/JNEUROSCI.1005-19.2019

Figure 2.

Figure 2.

Chemogenetic modulation of the CLA–PFC pathway did not affect locomotion. a, Representative figure showing chemogenetic modulation of the CLA–PFC pathway. b, Representative figures showing expression of hM3Dq-mCherry and hM4Di-mCherry in the CLA. c, Brain atlas showing microinjection sites. d, Representative figure showing cannulae placement and c-Fos expression in the PFC under low magnification (4× objective). e, Representative figures of c-Fos expression of different groups of rats under high magnification (20× objective). f, Chemogenetic activation and inhibition of the CLA–PFC pathway reduced and increased the number of c-Fos-positive cells in the PFC, respectively. g, Chemogenetic activation or inhibition of the CLA–PFC pathway did not affect locomotion. Data were presented s mean ± SEM n = 7/group. *p < 0.05, compared with saline group.