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. 2019 Dec 11;39(50):10002–10018. doi: 10.1523/JNEUROSCI.1234-19.2019

Figure 8.

Figure 8.

Changes in the odor responses of APC pyramidal neurons under passive exposure and go/go task conditions. A, Schema of the experimental paradigm. To record the odor-evoked calcium response of APC pyramidal neurons, AAV-expressing CaMKIIα-GCaMP6s was injected into the APC of C57 BL/6J mice. B, Expression of GCaMP6s in APC pyramidal neurons. C–E, Heat maps (C), trial-averaged traces (D), and ROC graph (E) of responses evoked by the two odors under passive exposure and go/go task conditions. F, Averaged traces of odor responses across all animal–odor pairs. G, Histograms and cumulative probability of auROCs under passive exposure (n = 14 animal–odor pairs from 9 mice) and go/go task conditions across all animal–odor pairs (n = 12 animal–odor pairs from 8 mice). H, I, Comparison of auROCs (H)/difference in ΔF/F (I) between the passive exposure and the go/go task conditions across all animal–odor pairs. H, Mann–Whitney test, n.s. (t = −0.463); (I) Mann–Whitney test, n.s. (z = −0.360).