Table 1.
Characteristics of study groups including healthy control cats, IRIS CKD stage 2 cats, and IRIS CKD stage 3 and 4 cats
| Healthy control cats (n = 11) | CKD stage 2 (n = 16) | CKD stages 3 and 4 (n = 12) | |
|---|---|---|---|
| Variable (reference interval) | Median (range) | Median (range) | Median (range) |
| Age (y) | 11 (8‐12)a | 15 (7‐22)b | 14.5 (7‐17.5) |
| BCS (1‐9) | 5 (4‐8) | 5 (3‐7) | 5 (2‐8) |
| MCS (0‐3) | 0 (0‐1)a | 1 (0‐2)b | 1 (0‐3)b |
| Fecal score (1‐7) | 2 (2) | 2 (1‐3) | 2 (2‐3) |
| Appetite score (0‐4) | 0 (0‐1)a | 1 (0‐3)b | 1 (0‐3)b |
| Vomiting score (0‐3) | 0 (0‐2)a | 2 (0‐3)b | 2 (0‐3) |
| Creatinine (0.8‐2.4 mg/dL) | 1.2 (0.7‐1.6)a | 2 (1.6‐2.6)b | 3.1 (2.9‐6.9)c |
| BUN (18‐35 mg/dL) | 24 (20‐38)a | 44 (20‐60)b | 54 (33‐98)b |
| Total calcium (9.2‐11.1 mg/dL) | 9.8 (9.1‐11.3)a | 10.1 (9.1‐10.7) | 10.5 (10‐11.4)b |
| Phosphorus (3.0‐6.0 mg/dL) | 4.3 (2.9‐5.0) | 3.7 (2.6‐5.6) | 4.4 (3.3‐8.1) |
| Potassium (3.7‐5.4 mEq/L) | 4.6 (4.2‐5.5) | 4.5 (3.9‐5.3) | 4.4 (4.1‐5.2) |
| Total T4 (1.2‐4.8 μg/dL) | 3.1 (1.9‐3.6)a | 2.0 (1.0‐3.7)b | 1.7 (1.0‐2.9)b |
Note: Rows with different superscript letters are significantly different from one another.
Abbreviations: BCS, body condition score; BUN, blood urea nitrogen; CKD, chronic kidney disease; IRIS, International Renal Interest Society; MCS, muscle condition score.