Table 3.
Clinical Predictors for 6-month favorable neurological outcomes in children with asphyxial out-of-hospital cardiac arrest who received therapeutic hypothermia.
| Characteristics | Favorable outcome (n = 8) | Unfavorable outcome (n = 26) | Univariate analysis | Multi-variate analysis | ||||
|---|---|---|---|---|---|---|---|---|
| Odd ratio | 95% CI | p-value | Odd ratio | 95% CI | p-value | |||
| Model 1 | ||||||||
| Initial lactate level | 59.72 ± 27.61 | 119.35 ± 53.85 | 0.954 | 0.914–0.995 | 0.030* | 0.941 | 0.886–0.999 | 0.048* |
| GCS++ | 5.75 ± 1.90 | 3.65 ± 1.29 | 2.079 | 1.230–3.515 | 0.006* | 2.179 | 1.058–4.486 | 0.035* |
| Model 2 | ||||||||
| Initial lactate level | 59.72 ± 27.61 | 119.35 ± 53.85 | 0.954 | 0.914–0.995 | 0.030* | 0.933 | 0.869–1.002 | 0.056 |
| GCS motor score ≥4++ | 5 (62.5%) | 4 (15.4%) | 9.16 | 1.539–54.592 | 0.015* | 33.689 | 0.782–1451.585 | 0.067 |
| Present pupil reflex++ | 6 (75%) | 7 (26.9%) | 8.14 | 1.320–50.250 | 0.024* | 1.007 | 0.044–20.051 | 0.966 |
GCS, Glasgow coma scale; CI, confidence interval.
Favorable outcome: pediatric cerebral performance category ≤ 2; Unfavorable outcome: pediatric cerebral performance category ≥3.
Examination before therapeutic hypothermia.
p < 0.05: statistical significant.