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. 2020 Jan 17;10:3002. doi: 10.3389/fimmu.2019.03002

Figure 1.

Figure 1

Data mining of the Tumor Immune Estimation Resource (TIMER) database. (A) Human KLRC1 expression levels in different tumor types from the TCGA database were determined by TIMER (*p < 0.05, **p < 0.01, ***p < 0.001). (B) Prognostic roles of KLRC1 and immune-related factors in lung adenocarcinoma (LUAD) from The Cancer Genome Atlas (TCGA) database were determined by TIMER. (C) Prognostic roles of KLRC1 and immune-related factors in lung squamous cell carcinoma (LUSC) from the TCGA database were determined by TIMER. (D) KLRC1 expression is significantly negatively related to tumor purity and has significant positive correlations with infiltrating levels of CD8+ T cells, macrophages, neutrophils, and dendritic cells in LUAD, but no significant correlations with infiltrating levels of B cells and CD4+ T cells. (E) KLRC1 expression is significantly positively correlated with tumor purity and infiltrating levels of B cells, CD8+ T cells, macrophages, neutrophils, and dendritic cells in LUSC, other than CD4+ T cells. (F) Correlation between KLRC1 and CD8A expression in LUAD. (G) Correlation between KLRC1 and CD8A expression in LUSC.