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. 2020 Jan 23;11:37. doi: 10.1186/s13287-020-1550-0

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — miR-455-3p is used to treat CCl4-induced acute liver injury in mice. a Experimental procedure in mice. b H&E staining of liver specimens. c CD68 immunohistochemistry. d Biochemical assays of hepatic indexes. e Flow cytometry analysis of the ratio of CD14 + CD16+ or CCR2 + CD16+ monocytes in peripheral blood CD45+ T cells. f Levels of inflammatory cytokines, chemokines, and growth factors in serum. Data are presented as the mean ± SEM (error bars). N = 5 mice per group; *p < 0.05, **p < 0.01, and ***p < 0.001. NC, miR-455-3p agomir negative control; miR, miR-455-3p agomir