Table 2. The top ten genes with the most obvious expression changes, screened by the identification of DEGs in three comparisons.

Category	Gene symbol	Log FC
		MUT vs WT	MUT vs control	WT vs control
Top ten upregulated genes in BRCA1/2-mutant breast cancer	CT45A10	4.46	7.66	3.22
	TBX10	3.94	6.63	2.61
	NLRP7	3.26	4.97	1.71
	BARHL2	3.24	5.40	2.15
	C4orf51	2.79	4.63	1.82
	CLLU1OS	2.68	4.15	1.47
	TUBB4A	2.67	4.14	1.43
	NPBWR1	2.32	4.16	1.83
	A2ML1	2.02	4.30	2.27
	TTK	1.00	3.68	2.68
Top ten downregulated genes in BRCA1/2-mutant breast cancer	MYOM2	−3.24	−5.64	−2.42
	CA4	−3.11	−8.48	−5.35
	LGALS12	−2.41	−6.47	−4.04
	SLC4A4	−2.07	−3.48	−1.37
	CAPN11	−1.91	−3.23	−1.36
	HPSE2	−1.90	−5.12	−3.23
	MAOA	−1.89	−4.55	−2.65
	DNAH9	−1.76	−3.21	−1.43
	RELN	−1.75	−4.40	−2.66
	NNAT	−1.55	−4.73	−3.16