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. 2020 Jan 21;8:e8252. doi: 10.7717/peerj.8252

Table 2. Association between MEX3A expression and clinical characteristics in liver cancer patients.

Clinical characteristics MEX3A expression
Variable No. of patients High % Low % χ2 p-value
Age <55 117 51 43.59 66 25.88 10.8573 0.001
>=55 255 66 56.41 189 74.12
Gender Female 121 43 36.75 78 30.47 1.1741 0.279
Male 252 74 63.25 178 69.53
Histological type Fibrolamellar Carcinoma 3 0 0 3 1.17 1.8006 0.547
Hepatocellular Carcinoma 363 114 97.44 249 97.27
Hepatocholangiocarcinoma (Mixed) 7 3 2.56 4 1.56
Histologic grade G1 55 10 8.7 45 17.79 20.0434 0.000
G2 178 48 41.74 130 51.38
G3 123 48 41.74 75 29.64
G4 12 9 7.83 3 1.19
stage I 172 48 43.64 124 51.88 2.1216 0.512
II 87 30 27.27 57 23.85
III 85 30 27.27 55 23.01
IV 5 2 1.82 3 1.26
T classification T1 182 49 41.88 133 52.36 4.9613 0.253
T2 95 35 29.91 60 23.62
T3 80 27 23.08 53 20.87
T4 13 6 5.13 7 2.76
TX 1 0 0 1 0.39
N classification N0 253 86 73.5 167 65.49 3.4688 0.135
N1 4 2 1.71 2 0.78
NX 115 29 24.79 86 33.73
M classification M0 267 88 75.21 179 69.92 2.0953 0.304
M1 4 2 1.71 2 0.78
MX 102 27 23.08 75 29.3
radiation therapy NO 340 106 98.15 234 97.5 0 1.000
Yes 8 2 1.85 6 2.5
Residual tumor R0 326 97 84.35 229 91.24 5.1533 0.134
R1 17 7 6.09 10 3.98
R2 1 0 0 1 0.4
RX 22 11 9.57 11 4.38
Vital status Deceased 130 55 47.01 75 29.3 10.3281 0.001
Living 243 62 52.99 181 70.7

Notes.

% represents the distribution of different clinical features in the single MEX3A expression group P-value in bold represent significant clinical significance (p < 0.05).