Table 5.
Multivariate logistic regression model of variables associated with objective response in the 138 patients with PanNET treated with TEM or TEM-CAP
| OR (95% CI) | p value | |
|---|---|---|
| TEM-CAP (vs. TEM alone) | 2.28 (0.91–5.69) | 0.077 |
| Ki-67 index (each additional 1%) | 0.98 (0.93–1.03) | 0.50 |
| WHO PS-1 or PS-2 (vs. WHO PS-0) | 0.21 (0.08–0.51) | 0.001 |
| Extrahepatic metastases (vs. absence) | 0.45 (0.22–0.90) | 0.024 |
| Previous treatment lines (each additional one) | 0.87 (0.60–1.27) | 0.47 |
Bold type denotes significance. PanNET, pancreatic neuroendocrine tumor; TEM, temozolomide; CAP, capecitabine; PS, performance status.