Table 6.
Multivariate Cox regression analysis of variables associated with the risk of death in the 138 patients with PanNET treated with TEM or TEM-CAP
| HR (95% CI) | p value | |
|---|---|---|
| TEM-CAP (vs. TEM alone) | 0.70 (0.36–1.38) | 0.30 |
| Ki-67 index (each additional 1%) | 1.04 (1–1.08) | 0.065 |
| WHO PS-1 or PS-2 (vs. WHO PS-0) | 1.82 (0.87–3.77) | 0.11 |
| Extrahepatic metastases (vs. absence) | 1.3 (0.79–2.14) | 0.30 |
| Previous treatment lines (each additional one) | 1.48 (1.14–1.92) | 0.003 |
Bold type denotes significance. PanNET, pancreatic neuroendocrine tumor; TEM, temozolomide; CAP, capecitabine; PS, performance status.