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. 2019 Jul 4;5(4):113–119. doi: 10.1136/bmjinnov-2018-000293

Table 3.

Lower 90% CI bound for PBE metric

Variable Lower bound
Log AUC collagen −0.01
Log Cmax collagen −0.02
Log AUC ASP-arachidonic acid 0.19*
Log Cmax ASP-arachidonic acid 0.16*
Log AUC salicylate 0.54*
Log Cmax salicylate 0.44

*Outside of range allowable to enable assumption of bioequivalence.

ASP, aspirin; AUC, area under the curve; PBE, population bioequivalence.