Fig. 2.

Effectiveness outcomes and responder rates. Effectiveness outcomes in absolute change (TLVR, RV, and SGRQ) and in relative change (FEV₁) from baseline to follow-up 6 weeks after EBV placement. Data are shown as median values (minimum to maximum). All p < 0.001. Wilcoxon signed rank test was used to calculate differences. Minimal clinically important difference (MCID) for TLVR was ≥563 mL reduction [10]; relevant change for FEV₁ ≥15% improvement; MCID for RV ≥430 mL reduction [11]; and MCID for SGRQ ≥7 points reduction [12]. It was not possible to obtain reliable body plethysmography measurement in 1 patient, with a TLVR on CT scan of −1,372 mL 6 weeks after EBV treatment.