. 2019 Nov 18;37(1):344–352. doi: 10.1007/s12325-019-01142-x

Table 2.

Cost-effectiveness in late stage knee OA

Treatment	ICER: 50% responder rate (versus HMW HA)	ICER: 10% responder rate (versus HMW HA)
HMW HA	–	–
LMW HA	Dominated	Dominated
Physical therapy and exercise	$36,875	$8027.03^a
Braces and orthosis	$11,600	$67,333.33
NSAID/analgesic medication	$67,000	Dominating

Dominated: HMW HA was both cheaper and more effective

Dominating: Treatment was both cheaper and more effective than HMW HA

^aIncremental cost of HMW HA and incremental effect were both negative, signifying that HMW HA is not cost-effective unless this ICER is greater than the willingness to pay threshold