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. 2019 Oct 30;37(1):41–60. doi: 10.1007/s12325-019-01128-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Reduced a exertional breathlessness during constant-load cycle exercise after exercise training (EXT) or control intervention in patients with COPD. Slopes of b carbon dioxide output (VCO₂), c ventilation (V_E), and d breathing frequency also fell significantly after EXT. *p < 0.05. COPD chronic obstructive pulmonary disease, EXT exercise training, F breathing frequency, VCO₂ carbon dioxide production, V_E minute ventilation, V_T tidal volume.

Reprinted with permission of the American Thoracic Society. Copyright © 2019 American Thoracic Society. O’Donnell DE, McGuire M, Samis L, Webb KA. 1998. General exercise training improves ventilatory and peripheral muscle strength and endurance in chronic airflow limitation. Am J Respir Crit Care Med. 157(5):1489–1497. The American Journal of Respiratory and Critical Care Medicine is an official journal of the American Thoracic Society