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Canadian Journal of Public Health = Revue Canadienne de Santé Publique logoLink to Canadian Journal of Public Health = Revue Canadienne de Santé Publique
. 2001 Jul 1;92(4):250–254. doi: 10.1007/BF03404954

Trends of Hepatitis B and Hepatitis C Mortality in Canada, 1979–1997

Gina Pohani 1, Shimian Zou 1,
PMCID: PMC6979656  PMID: 11962107

Abstract

Mortality data from Statistics Canada were analyzed to measure the temporal trends and burden of illness attributed to viral hepatitis in Canada. Analysis of age-standardized mortality rates from 1979 to 1997 showed an increasing trend in mortality for both hepatitis B and non-A, non-B hepatitis (NANBH), most of which are attributed to hepatitis C infections. Hepatitis B and NANBH agestandardized mortality rates increased respectively, from 0.03 and 0.12 deaths per 100,000 population in 1979 to 0.26 and 0.41 deaths per 100,000 in 1997. Male mortality rates were consistently higher than female for both diseases. Among deaths from chronic liver disease, over 1,000 deaths were estimated to have been caused by hepatitis B and hepatitis C annually. Although the hepatitis B or NANBH recorded deaths largely underestimate the true burden of HBV and HCV in Canada, the temporal trends are useful as they reflect changes in the impact of both diseases.

References

  • 1.Edmunds WJ, Medley GF, Nokes DJ, et al. Epidemiological patterns of hepatitis B virus (HBV) in highly endemic areas. Epidemiol Infect. 1996;117(2):313–325. doi: 10.1017/S0950268800001497. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.World Health Organization. World Health Report: Life in the 21st Century: A Vision for All. Geneva: WHO; 1998. [Google Scholar]
  • 3.Hadler SC, Margolis H. Hepatitis B immunization: Vaccine types, efficacy, and indications for immunization. Current Clinical Topics In Infectious Diseases. 1992;12:282–308. [PubMed] [Google Scholar]
  • 4.Tepper ML, Gully P, Hepatitis B. CMAJ. 1997;156:1033. [PMC free article] [PubMed] [Google Scholar]
  • 5.Remis RS, Hogg R, Krahn MD, et al. Estimating the number of blood transfusion recipients infected with hepatitis C in Canada 1960–85 and 1990–92. 1998. [Google Scholar]
  • 6.Zou S, Tepper M, El Saadany S. Prediction of hepatitis C burden in Canada. Can J Gastroenterol. 2000;14(7):575–80. doi: 10.1155/2000/642707. [DOI] [PubMed] [Google Scholar]
  • 7.Global surveillancecontrol of hepatitis C. Report of a WHO consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium. J Viral Hepatitis. 1999;6:35–47. doi: 10.1046/j.1365-2893.1999.6120139.x. [DOI] [PubMed] [Google Scholar]
  • 8.Maddrey WC. Hepatitis B: An important public health issue. J Med Virology. 2000;61(3):362–66. doi: 10.1002/1096-9071(200007)61:3<362::AID-JMV14>3.0.CO;2-I. [DOI] [PubMed] [Google Scholar]
  • 9.Chin J, editor. Control of Communicable Diseases Manual. 17th. Washington, DC: American Public Health Association; 2000. [Google Scholar]
  • 10.MMWR. Recommendations for Prevention and Control of Hepatitis C Virus (HCV) Infection and HCV-Related Chronic Disease. 1998;47(RR-19):1–36. [PubMed] [Google Scholar]
  • 11.Alter MJ. The epidemiology of acute and chronic hepatitis C. Clin Liver Disease. 1997;1:559–68. doi: 10.1016/S1089-3261(05)70321-4. [DOI] [PubMed] [Google Scholar]
  • 12.Statistics Canada. Causes of Death. Ottawa: Health Statistics Division; 1979. [Google Scholar]
  • 13.World Health Organization. International Classification of Diseases. 1977. [Google Scholar]
  • 14.Myers KA, Farquhar D. Improving the Accuracy of Death Certification. CMAJ. 1998;159(10):1317–23. [PMC free article] [PubMed] [Google Scholar]
  • 15.http://www.cehip.org/DataArea/New%20Folder/mortality.htm. Accessed 06/08/2000.
  • 16.Statistics Canada. Census of Canada. 1991. [Google Scholar]
  • 17.Dana F, Becherer PR, Bacon BR. Hepatitis C virus, What recent studies can tell us. Postgraduate Medicine. 1994;95:121–30. doi: 10.1080/00325481.1994.11945847. [DOI] [PubMed] [Google Scholar]
  • 18.Hollinger FB, Dienstag JL. Manual of Clinical Microbiology. Washington, DC: American Society for Microbiology; 1985. Hepatitis Viruses; pp. 813–823. [Google Scholar]
  • 19.National Notifiable Disease Reporting System. Laboratory Centre for Disease Control. Health Canada. 1999. [Google Scholar]
  • 20.Alter MJ, Shapiro CN, Coleman PJ, Margolis HS. Viral Hepatitis in North America. In: Nishioka K, editor. Viral Hepatitis and Liver Disease. Tokyo, New York: Springer-Verlag; 1994. pp. 439–443. [Google Scholar]
  • 21.Margolis HS, Alter MJ, Hadler SC, et al. Hepatitis B: Evolving epidemiology and implications for control. Semin Liver Dis. 1991;11:84–92. doi: 10.1055/s-2008-1040427. [DOI] [PubMed] [Google Scholar]
  • 22.Statistics Canada. Immigrant Population, by Place of Birth Showing Periods of Immigration, 1996 Census. CANSIM Utility. Ottawa: Statistics Canada; 1996. [Google Scholar]
  • 23.Statistics Canada. Immigrant Population, by Place of Birth, 1996 Census. CANSIM Utility. Ottawa: Statistics Canada; 1996. [Google Scholar]
  • 24.Alter MJ. Epidemiology of hepatitis C in the west. Semin Liver Dis. 1995;15(1):5–14. doi: 10.1055/s-2007-1007259. [DOI] [PubMed] [Google Scholar]
  • 25.Colquhoun SD. Hepatitis C: A clinical update. Arch Surg. 1996;131:18–23. doi: 10.1001/archsurg.1996.01430130020004. [DOI] [PubMed] [Google Scholar]
  • 26.Zou S, Tepper M, Giulivi A. Can J Public Health. 2000. Current status of hepatitis C in Canada; pp. S10–S15. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 27.Zou S, Zhang J, Tepper M, et al. Can J Infect Dis. 2001. Enhanced surveillance of acute hepatitis B and acute hepatitis C in four health regions in Canada. [DOI] [PMC free article] [PubMed] [Google Scholar]

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