Bar graph (mean +/− SEM) depicting astrocytic ATP content (ng) per 10,000 cells for astrocytes incubated under normoxia (n = 18), 3-hours hypoxia (n = 12), and 3-hours hypoxia then 10-hours reoxygenation (n = 24) (A). Mitochondrial superoxide production during normoxia, after hypoxia and throughout post-hypoxia reoxygenation (B). Quasi bar graph and line graph (mean +/− SEM) depicting the time-dependent superoxide production by mitochondria during normoxia (n = 24), hypoxia (n = 21), and for 0.5, 1, 2, 4, 8, and 12-hours reoxygenation (n = 22). Panel A was analyzed by a one-way ANOVA, Bonferroni’s multiple comparison test was used to determine the level of significance between the experimental groups (***p < 0.0001). Panel B was assessed by one-way ANOVA, Dunnett’s post-hoc test was used to determine the level of significance between the experimental groups (*p < 0.05; ***p < 0.0001).