. Author manuscript; available in PMC: 2020 Jan 24.

Published in final edited form as: J Chem Theory Comput. 2014 Feb 11;10(2):524–533. doi: 10.1021/ct400606c

Table 1.

Operational Comparison of the Mean Forces and Swarms-of-Trajectories String Methods^a

	mean forces	swarms of trajectories
0	build initial path	build initial path
1	restrained sampling to estimate mean forces	short restrained sampling to prepare swarms
2		run swarms
3	evolve collective variables with estimate of mean forces	evolve collective variables with estimate of drift
4	reparametrization	reparametrization

Steps 1 to 4 are performed at each image and iterated until convergence.