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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: J Orthop Res. 2019 Sep 18;38(2):405–416. doi: 10.1002/jor.24461

Figure 1.

Figure 1.

Bone marrow macrophages from young and aged mice were polarized to M1 or M2 phenotype with IFN-γ or IL-4, respectively, or left untreated as non-polarized M0 macrophages. The mRNA expressions of (a) IL-6, (b) IL-1β, (c) IL-1Ra, (d) iNOS, (e) CCL2, (f) TLR4, (g) CXCL9, (h) MRC1, and (i) TNF were determined 30 hours after the induction of polarization by qRT-PCR. * indicates statistical significance between similarly polarized young and aged macrophages, whereas # illustrates significant difference between polarizations within the same age group. $ stands for significant difference between M0 and M2 phenotype in both age groups.