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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Ann Neurol. 2019 Dec 5;87(2):267–280. doi: 10.1002/ana.25649

TABLE 2.

Effects of Independent Variables on Longitudinal Awareness

Variable Estimate SE df t P
Intercept 1.82 0.33 4,527 5.47 <0.001a
Baseline age −0.02 0.003 4,527 −4.42 <0.001a
Baseline Aβ −0.44 0.13 4,527 −3.53 <0.001a
Time 0.55 0.10 4,527 5.22 <0.001a
Female sex 0.07 0.05 4,527 1.28 0.20
APOEε4+ −0.008 0.06 4,527 −0.14 0.89
Years of education 0.01 0.009 4,527 1.33 0.18
Baseline DX −1.08 0.09 4,527 −12.62 <0.001a
Baseline age:time −0.003 0.001 4,527 −2.82 0.005b
Baseline Aβ:time −0.22 0.04 4,527 −5.42 <0.001a
Time:female sex −0.007 0.02 4,527 −0.42 0.67
Time:APOEε4+ −0.05 0.02 4,527 −2.68 0.007b
Time:years of education −0.005 0.003 4,527 −1.65 0.10
Time:baseline DX −0.07 0.03 4,527 −2.21 0.03b
a

p < 0.001.

b

p < 0.05.

APOEε4 = apolipoprotein E4 genotype; Aβ = beta-amyloid; DX = diagnosis; SE = standard error.