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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Ann Neurol. 2019 Dec 5;87(2):267–280. doi: 10.1002/ana.25649

TABLE 5.

Effect of Amyloid on Longitudinal Awareness Within Each Diagnostic Group

Estimate SE df t P
CN
 Intercept 0.63 0.33 1,457 1.91 0.06a
 Baseline age −0.007 0.004 1,457 −1.65 0.10
 Baseline Aβ 0.16 0.15 1,457 1.11 0.27
 Time 0.26 0.12 1,457 2.10 0.04a
 Baseline age:time −0.002 0.001 1,457 −1.24 0.22
 Baseline Aβ:time −0.12 0.05 1,457 −2.36 0.02a
MCI
 Intercept 1.93 0.36 2,792 5.36 <0.001b
 Baseline age −0.01 0.005 2,792 −2.99 0.003a
 Baseline Aβ −0.73 0.16 2,792 −4.65 <0.001b
 Time 0.46 0.11 2,792 4.25 <0.001b
 Baseline age:time −0.002 0.001 2,792 −1.70 0.09
 Baseline Aβ:time −0.30 0.05 2,792 −6.03 <0.001b
Dementia
 Intercept −0.48 1.05 295 −0.46 0.65
 Baseline age −0.01 0.01 295 −1.03 0.30
 Baseline Aβ 0.07 0.36 295 0.20 0.84
 Time 0.41 0.59 295 0.69 0.49
 Baseline age:time 0.002 0.007 295 0.30 0.76
 Baseline Aβ:time −0.57 0.19 295 −3.06 0.002a
a

p < 0.05.

b

p < 0.001.

Aβ = beta-amyloid; CN = clinically normal; MCI = mild cognitive impairment; SE = standard error.