Fig. 2.

Associations in the VEGF family with cognition, AD dementia, and AD pathology. This figure presents an illustration of the VEGF family, with arrows drawn from each ligand to each receptor/co-receptor with which it binds. Gene expression levels of the ligands and receptors in color (VEGFB, PGF, FLT4, and FLT1) were associated with worsening cognitive performance prior to death and associated with amyloid or tau pathology at autopsy. Asterisk indicates genes that were expressed differently between participants with AD dementia and those with normal cognition