Figure 2.
CAMKII inhibition with tat-CN19o provides neuroprotection from CA/CPR induced Purkinje cell loss. A. Representative images of calbindin labeling used to quantify Purkinje cell density in the cerebellum at 7 days after CA/CPR. B. Quantification of Purkinje cell densities at 7 days after surgery. Mice that were subjected to CA/CPR and received tat-scr or 0.01 mg/kg tat-CN19o had lower cell densities. Tat-CN19o doses of 0.1 and 1.0 mg/kg had similar cell density to sham controls. N=4–8 per group. One-way ANOVA with Tukey multiple comparisons. * indicates p<0.05. ** indicates p<0.01.
