Table 4. Crude and multivariable-adjusted ORs and 95% CIs for IBS subgroups across categories of whole-day water intakea.
| Whole-day water intake (n. of glasses/d) | |||||
|---|---|---|---|---|---|
| <2 | 2–5 | 6–8 | >8 | P-trend | |
| IBS-C | |||||
| Crude | 1.00 | 1.03 (0.80–1.34) | 0.69 (0.48–1.00) | 0.36 (0.16–0.79) | 0.004 |
| Model Ib | 1.00 | 1.17 (0.88–1.54) | 0.76 (0.50–1.15) | 0.48 (0.20–1.12) | 0.09 |
| Model IIc | 1.00 | 1.14 (0.84–1.54) | 0.82 (0.52–1.28) | 0.58 (0.24–1.37) | 0.24 |
| Model IIId | 1.00 | 1.13 (0.83–1.55) | 0.86 (0.55–1.35) | 0.51 (0.20–1.30) | 0.25 |
| IBS-D | |||||
| Crude | 1.00 | 0.83 (0.59–1.16) | 0.95 (0.62–1.44) | 0.87 (0.44–1.73) | 0.71 |
| Model Ib | 1.00 | 0.79 (0.54–1.13) | 0.91 (0.56–1.45) | 1.10 (0.54–2.22) | 0.94 |
| Model IIc | 1.00 | 0.99 (0.65–1.51) | 1.32 (0.79–2.22) | 1.58 (0.75–3.32) | 0.14 |
| Model IIId | 1.00 | 0.98 (0.64–1.50) | 1.34 (0.79–2.25) | 1.69 (0.80–3.57) | 0.10 |
| IBS-M | |||||
| Crude | 1.00 | 0.94 (0.66–1.34) | 0.93 (0.59–1.46) | 1.46 (0.79–2.69) | 0.55 |
| Model Ib | 1.00 | 0.85 (0.59–1.24) | 0.89 (0.55–1.46) | 1.39 (0.71–2.71) | 0.70 |
| Model IIc | 1.00 | 0.84 (0.56–1.27) | 1.01 (0.59–1.72) | 1.64 (0.81–3.39) | 0.32 |
| Model IIId | 1.00 | 0.93 (0.60–1.43) | 1.12 (0.65–1.95) | 2.07 (1.01–4.22) | 0.11 |
| IBS-U | |||||
| Crude | 1.00 | 1.07 (0.79–1.44) | 1.18 (0.81–1.71) | 0.51 (0.23–1.14) | 0.70 |
| Model Ib | 1.00 | 1.13 (0.82–1.56) | 1.25 (0.83–1.89) | 0.62 (0.26–1.46) | 0.88 |
| Model IIc | 1.00 | 1.07 (0.75–1.52) | 1.36 (0.88–2.12) | 0.72 (0.30–1.73) | 0.57 |
| Model IIId | 1.00 | 1.02 (0.72–1.46) | 1.28 (0.81–2.00) | 0.72 (0.30–1.74) | 0.73 |
aValues are OR (95% CIs).
bAdjusted for age and sex.
cAdditionally adjusted for marital status, smoking status, supplement use, depression, GI medications use and antipsychotic medications use.
dAdditionally, adjusted for meal pattern regularity and dental status.
IBS: Irritable Bowel Syndrome; IBS-C: IBS with constipation; IBS-D: IBS with diarrhea; IBS-M: mixed IBS; IBS-U: unsubtyped IBS.