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. 2020 Jan 24;15(1):e0227554. doi: 10.1371/journal.pone.0227554

Fig 7. Differential function of 5-HT receptors in GABAergic neurons and PNs in odorant attraction.

Fig 7

A, The expression of 5-HT1B RNAi in the LNs using the GAD1-Gal4 driver inhibited the attractive response to 0.0125% AA-enriched food odor blends, while 5-HT1B RNAi expressed in the PNs by using the GH146-Gal4 driver did not result in significant differences from the controls (N = 26–34). B, The attraction to 3% AA was increased by expression of 5-HT1B RNAi in the GABAergic neurons compared to the attraction in genetic controls (N = 30). C, The expression of 5-HT1B RNAi in the GABAergic neurons or PNs had no effect on 0.025% EtOAc attraction (N = 23–24). D, No differences in 0.0125% AA attraction was observed when the RNAi of 5-HT1A was expressed in the GABAergic or PNs compared to 0.0125% AA attraction in genetic controls (N = 24–26). E—F, The expression of 5-HT1A (E) or 5-HT2A (F) RNAi in the PNs induced a significant increase in 3% AA attraction compared to controls (N = 22–29). The star indicates a significant difference as determined by one-way ANOVA followed by post hoc Tukey-Kramer analysis (P* < 0.05), and the letter a indicates a significant difference from random choice as determined by One-sample sign test (P < 0.05). For the underlying numerical data see S7 Table.