Table 3. Comparison of gait parameters for the most and least affected sides in the in PD-GBA and non-GBA in the OFF-medication condition and healthy controls.
PD-GBA | Non-mutation carriers | Healthy Controls | p-value | ||
---|---|---|---|---|---|
Arm swing velocity (degrees/s) | Most affected | 156.6 ± 62.2 | 110.9 ± 69.7 | 168.6 ± 48.4 | 0.059+ |
Least affected | 155 ± 38.8 | 140.5 ± 38.7 | 0.299+ | ||
p-value | 0.929 | 0.148 | |||
Arm range of motion (degrees) | Most affected | 31.4 ± 15.4 | 15.7 ± 7.1 | 39.8 ± 15.0 | 0.001+ |
Least affected | 33.1 ± 11.6 | 29.7 ± 12.8 | 0.430+ | ||
p-value | 0.725 | 0.001 | |||
Stride length (m) | Most affected | 1.1 ± 0.1 | 1.0 ± 0.18 | 1.2 ± 0.11 | 0.406+ |
Least affected | 1.1 ± 0.11 | 1.0 ± 0.2 | 0.060+ | ||
p-value | 0.508 | 0.630 |
Gait parameters and their asymmetry in PD-GBA vs. non-GBA subjects for most and least affected sides in the OFF state. Mean of both body sides were calculated in controls.
+:p-values are comparing GBA carriers and non-GBA carriers; GBA = glucocerebrosidase.