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(A) Viability of parental NCI-H520 and its prexasertib-resistant version (NCI-H520R) was evaluated following prexasertib treatment for 96 hours. (B) Analysis of selected cell cycle-related proteins extracted from DMSO- or prexasertib-treated cultures for 24 hours. Drug concentrations used: 0, 6.25, 12.50, 25, 50, and 100 nM.
