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. 2020 Jan 21;11(3):216–236. doi: 10.18632/oncotarget.27400

Figure 8. GSEA of transcriptomic data from seven cancer cell lines with acquired resistance to prexasertib.

Figure 8

Gene expression analysis was carried out on replicate (mostly triplicate) parental/resistant cultures using RNASeq (four ovarian cancer cell lines) and microarrays (NCI-H520, SJC-Rh30 and Rh41). Expression data was normalized as described in Methods and subject to GSEA as described by Subramanian [19].