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. Author manuscript; available in PMC: 2021 Jan 16.
Published in final edited form as: Cell Chem Biol. 2019 Nov 14;27(1):57–65.e9. doi: 10.1016/j.chembiol.2019.10.013

Figure 3 |. ZNL-02-096 induces DNA damage, apoptosis, and premature mitosis.

Figure 3 |

(A) Immunoblot analysis of MOLT4 cells treated with the ZNL-02-096, ZNL-02-178, AZD1775, or pomalidomide for 24 hrs. (B) MOLT4 cells treated with ZNL-02-096, ZNL-02-178, or AZD1775 for the indicated time points and stained with propidium iodide. Reported as mean ± SEM for n=3 biological replicates; (C) Parental or CRBN−/− MOLT4 cells treated with ZNL-02-096, ZNL-02-178, AZD1775, or Lenalidomide for 24 hrs and stained with propidium iodide. Reported as mean ± SEM for n=3 biological replicates.