Table 1.

Species considered in the model and their symbols.

Notation	Description
HL	Holo-Lf, iron-loaded lactoferrin, in the blood side
R1	High-affinity binding sites (receptors)
HR1,am	Holo-Lf bound with high-affinity receptors on the apical membrane
R2	Low-affinity binding sites (receptors)
HR2,am	Holo-Lf bound with low-affinity receptors on the apical membrane
AL	Apo-Lf, iron-free lactoferrin, in the blood side
AR1,am	Apo-Lf bound with high-affinity receptors on the apical membrane
AR2,am	Apo-Lf bound with low-affinity receptors on the apical membrane
HR1,i	Holo-Lf bound with high-affinity receptors inside the cell
AR1,i	Apo-Lf bound with high-affinity receptors inside the cell
Fei	Free iron inside the cell
Fes	Iron stored as ferritin
Feu	Iron utilized by the organelles of cell
Febr	Iron transported to the brain side
Fe	Iron transported to blood side
HR1,bm	Holo-Lf bound with high-affinity receptors on the basolateral membrane
AR1,bm	Apo-Lf bound with high-affinity receptors on the basolateral membrane
R1,bm	Receptor associated with basolateral membrane
HLbr	Holo-Lf transported to the brain side
ALbr	Apo-Lf transported to the brain side