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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Biochim Biophys Acta Gen Subj. 2019 Nov 1;1864(3):129459. doi: 10.1016/j.bbagen.2019.129459

Table 4.

Performance of Markov chain Monte Carlo scheme with various sampling variances. Although the mean varies largely from low variance to high variance, all sampling variances yield similar mode and median. In this study, mode is used as point estimate of parameters in the mass-action based mathematical model.

Hyperparameter, a
Accepted steps

Total steps

Acceptance rate
Statistics of parameter k1 [cm5 / (nmol.sec)]

Mean

Median

Mode
Standard deviation
95% Credible interval

2

2×105
2.30×105
87.0%
7.38×10−3 7.32×10−3 7.27×10−3
6.68×10−4

6.07×10−3 −8.67×10−3

5

2×105
3.71×105
53.9%
7.51×10−3 7.52×10−3 7.59×10−3
6.52×10−4

6.23×10−3 −8.79×10−3

7

2×105
4.74×105
42.2%
1.21×10−2 8.06×10−3 7.48×10−3
1.203×10−2

0.0 – 6.023×10−2