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MCF disrupts the mitochondrial network.
A. Cos7 cells were incubated with MitoTracker™ Green FM to visualize mitochondria prior to infection with CMCP6 rtxA1::bla or CMCP6 rtxA1::mcf-bla at a MOI of 5 for an hour. Images taken prior to intoxication and every 10 minutes after. Insets show enlarged image of one cell for each condition at 60 minutes. Additional cells are shown in Supplemental Fig. 6.
