Table 1.

Demographics and clinical parameters of subjects with T1D and non-diabetic controls. Values are presented as mean ± SD (range) or n (%).

	Control (n=74)	T1D (n=175)	p-value*
Age (yrs)	15.4 ± 2.2 (12.0 − 20.0)	15.2 ± 2.2 (12.0 − 19.4)	0.547
Sex (%female)	42 F/ 32 M (56.8%)	99 F/ 76 M (56.6%)	1.000
Tobacco Use Now	6 (8.1%)	12 (6.9%)	0.790
HbA1c (%)	5.3 ± 0.3 (4.6 − 5.9)	9.0 ± 1.6 (5.8 − 14.0)	< 0.001
Fasting glucose (mg/dL)	82±7(64 − 99)	185 ± 80 (40 − 451)	< 0.001
C-peptide (ng/mL)	1.7 ± 0.6 (0.1 − 3.3)	0.1 ± 0.1 (0.1 − 1.3)	< 0.001
BMI (kg/m2)	21.8 ± 4.2 (13.8 − 33.5)	22.4 ± 3.4 (15.3 − 35.3)	0.259
Hs-CRP (mg/dL)	0.9 ±1.4 (0.0 – 6.4)	1.3 ± 2.3 (0.1 – 22.0)	0.084
TG (mg/dL)	83.5 ± 41.5 (34.0 − 235.0)	86.8 ± 50.5 (28.0 − 333.0)	0.586
TC (mg/dL)	147.7 ± 28.0 (96.0 − 235.0)	159.4 ± 34.8 (89.0 − 347.0)	0.006
LDL-C (mg/dL)	82.4 ± 22.9 (43.0 − 168.0)	89.9 ± 27.8 (42.0 − 250.0)	0.028
HDL-C (mg/dL)	48.6 ± 9.3 (28.0 − 74.0)	52.1 ± 10.6 (30.0 − 81.0)	0.010
SBP (mmHg)	109.0 ± 8.5 (89.0 − 129.0)	113.1 ± 8.5 (93.0 − 137.0)	< 0.001
DBP (mmHg)	64.3 ± 6.1 (49.0 − 79.0)	69.0 ± 6.5 (50.0 − 89.0)	< 0.001
Campesterol (A.U.)	1.00 ± 0.35 (0.41 – 1.95)	1.31 ± 0.41 (0.47 – 2.60)	< 0.001
β-Sitosterol (A.U.)	1.00 ± 0.36 (0.39 – 2.25)	1.29 ± 0.44 (0.50 – 2.72)	< 0.001
Lathosterol (A.U.)	1.00 ± 0.51 (0.32 – 2.52)	0.79 ± 0.38 (0.26 – 2.77)	0.001

^*p-value based on t-tests or Fisher’s exact test. Boldface type highlights statistical significance with p<0.05.