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. 2020 Jan 20;13:559–571. doi: 10.2147/OTT.S222375

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© 2020 Li et al.

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Interaction between LncRNA MALAT1 and miR-22-3p. (A) A binding site predicated by StarBase (http://starbase.sysu.edu.cn/); (B) A target interaction identified by DLR assay; (C) Relative miR-22-3p expression in gastric cancer (GC) tissues and adjacent normal tissues at the mRNA level (N = 37); (D) Relative MALAT1 expression in GC cell lines, SGC-7901 and BGC-823 and a normal human gastric mucosal epithelial cell line, GES-1 at the mRNA level; (E) Correlation analysis of the relationship between MALAT1 and miR-22-3p in GC tissues (N = 37); (F) Relative miR-22-3p expression in transfected SGC-7901 and BGC-823 cells. pcDNA-NC, pcDNA-MALAT1 negative control; si-MALAT1, siRNA-MALAT1; si-MALAT1 NC, siRNA-MALAT1 negative control. Each experiment was performed in three replicates. *P < 0.05 vs mimics NC (B), adjacent tissues (C), GES-1 (D), and pcDNA-NC (F); ^#P < 0.05 vs si-MALAT1 NC.