Table 2.
Veteran Comorbidities by CPT/PE Initiation and Timing
| Early EBP n=19,755 | Delayed EBP n=40,879 | No EBP n=204,932 | ||||||
| n | % | n | % | n | % | pc | Significant Pair-wise Comparisonsd | |
| Bipolar Disorder | 2,048 | 10.4% | 7,202 | 17.6% | 25,414 | 12.4% | <0.001 | E vs. D D vs. N E vs. N |
| Depressive Disorder | 12,605 | 63.8% | 30,947 | 75.7% | 126,028 | 61.5% | <0.001 | E vs. D D vs. N E vs. N |
| Other Psychotic Spectrum Disorder | 406 | 2.1% | 1,613 | 4.0% | 5,975 | 2.9% | <0.001 | E vs. D D vs. N E vs. N |
| Pain Disorder | 14,708 | 74.5% | 34,473 | 84.3% | 149,570 | 73.0% | <0.001 | E vs. D D vs. N E vs. N |
| Schizophrenia | 148 | 0.8% | 581 | 1.4% | 3,062 | 1.5% | <0.001 | E vs. D E vs. N |
| Any Substance Use Disorderd | 6,018 | 30.5% | 17,992 | 44.0% | 67,021 | 32.7% | <0.001 | E vs. D D vs. N E vs. N |
| Alcohol Abuse | 4,065 | 20.6% | 12,690 | 31.0% | 43,126 | 21.0% | <0.001 | E vs. D D vs. N |
| Alcohol Dependence | 3,133 | 15.9% | 10,456 | 25.6% | 31,596 | 15.4% | <0.001 | E vs. D D vs. N |
| Drug abuse | 2,246 | 11.4% | 8,688 | 21.3% | 26,631 | 13.0% | <0.001 | E vs. D D vs. N E vs. N |
| Drug Dependence | 1,799 | 9.1% | 7,311 | 17.9% | 21,264 | 10.4% | <0.001 | E vs. D D vs. N E vs. N |
| Suicidal Ideation or Attempt | 2,269 | 11.5% | 7,813 | 19.1% | 21,367 | 10.4% | <0.001 | E vs. D D vs. N E vs. N |
| Traumatic Brain Injury | 3,519 | 17.8% | 8,536 | 20.9% | 28,519 | 13.9% | <0.001 | E vs. D D vs. N E vs. N |
| Categorical Number of Comorbidities | <0.001 | E vs. D D vs. N |
||||||
| 0 Comorbidities | 1,745 | 8.8% | 1,402 | 3.4% | 18,511 | 9.0% | ||
| 1 Comorbidity | 4,909 | 24.9% | 6,170 | 15.1% | 51,347 | 25.1% | ||
| 2+ Comorbidities | 13,101 | 66.3% | 33,307 | 81.5% | 135,074 | 65.9% | ||
| M | SD | M | SD | M | SD | pb | Significant Pair-wise Comparisonsc | |
| Continuous Number of Comorbidities | 2.4 | 1.8 | 3.2 | 2.1 | 2.4 | 1.8 | <0.001 | E vs. D D vs. N |
Note. CPT, cognitive processing therapy; PE, prolonged exposure therapy.
a
For categorical variables, p values are based on Chi-Square. For number of comorbidities, (continuous variable), p value is based on the Kruskal Wallis test.
b
Pair-wise comparisons used Chi-Square for categorical variables and Mann-Whitney test for continuous variables. To correct for multiple statistical tests, statistical significance level was set to p < 0.0003 (i.e., p < 0.001/3)
c
Any substance use disorder refers to the presence of any alcohol/drug abuse and/or dependence.