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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: J Neurochem. 2019 Aug 22;152(3):381–396. doi: 10.1111/jnc.14834

Figure 3. Sex and genotype effects on liver iron uptake.

Figure 3

A) H67D mice take up significantly more 59Fe-Tf into the liver on PND22. Wild-type mice take up significantly more 59Fe-FtH1 into the liver uptake on PND14 (n=10 mice). B) Female wild-type mice take up significantly more 59Fe-Tf into their livers on PND7 than their respective H67D counterparts, but on PND22 H67D mice livers take up significantly more 59Fe-Tf. C) Male wild-type mice take up significantly more 59Fe-FtH1 at PND7 than H67D mice, while female H67D mice take up significantly more 59Fe-FtH1 on PND22 than wild-type female mice. For B) and C), n=5 mice for males and n=5 mice for females; means from all biological replicates ± SD were evaluated for statistical significance using two-way ANOVA with Bonferroni’s posttest for significance. *=p<0.05.