Table 2.
Associations of overweight/obesity (OW/OB) with high or low meteabolic risk (MetRisk) with metabolite factor scores.
| β (95% CI) | P-value | ||||
|---|---|---|---|---|---|
| Non-OWOB & Low MetRisk | Non-OWOB & High MetRisk | OWOB & Low MetRisk | OWOB & High MetRisk | ||
| n=335 | n=29 | n=58 | n=102 | ||
| Factor 1 | 0.00 (Reference) | −0.90 (−1.39, −0.42) | 0.27 (−0.09, 0.63) | −0.27 (−0.56, 0.02) | 0.0002* |
| Factor 2 | 0.00 (Reference) | 0.13 (−0.85, 1.11) | −0.37 (−1.10, 0.35) | 0.01 (−0.57, 0.59) | 0.75 |
| Factor 3 | 0.00 (Reference) | 0.04 (−0.64, 0.71) | −0.12 (−0.61, 0.38) | −0.32 (−0.72, 0.08) | 0.47 |
| Factor 4 | 0.00 (Reference) | −0.01 (−0.88, 0.85) | −0.38 (−1.02, 0.26) | −0.32 (−0.84, 0.19) | 0.48 |
| Factor 5 | 0.00 (Reference) | 0.25 (−0.42, 0.91) | −0.06 (−0.55, 0.43) | 0.58 (0.17, 0.98) | 0.03 |
| Factor 6 | 0.00 (Reference) | 0.07 (−0.74, 0.88) | −0.32 (−0.92, 0.28) | −0.17 (−0.65, 0.31) | 0.70 |
| Factor 7 | 0.00 (Reference) | 0.47 (0.04, 0.91) | −0.36 (−0.68, −0.04) | −0.13 (−0.39, 0.12) | 0.01 |
| Factor 8 | 0.00 (Reference) | 0.75 (−0.04, 1.54) | 0.11 (−0.47, 0.69) | 0.88 (0.42, 1.35) | 0.001* |
| Factor 9 | 0.00 (Reference) | −0.03 (−0.50, 0.45) | 0.25 (−0.10, 0.60) | 0.44 (0.16, 0.72) | 0.01 |
a
Estimates are adjusted for age, sex, race/ethnicity, and pubertal status. OWOB is defined as ≥85th percentile of age- and sex-specific BMI according to the CDC 2000 growth reference; high MetRisk defined as being in the 4th quartile of an externally standardized metabolic syndrome risk z-score.
Bold font indicates statistical significance at alpha = 0.05.
*
Denotes statistical significance after Bonferroni correction (P < α < 0.05/9=0.006)