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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Clin Pharmacol Ther. 2019 Oct 20;107(2):462–470. doi: 10.1002/cpt.1629

Figure 3. Incidence rate of acute kidney injury by tacrolimus exposure intensity.

Figure 3.

Tacrolimus time-lagged average concentration on each day was classified into bins of concentration as follows: <8 ng/ml, 8–12 ng/ml, > 12 ng/ml. The rate of AKI was then calculated within each bin of person time as the number of AKI events / total person time within that range. Because baseline AKI rate varied substantially over time, analysis was stratified by time. a- AKI rate during post-operative days 0–3. b. AKI rate during post-operative days 4–14.