Table III.
Predictors of approval of a prospective interventionist to enter patients in the stenting trial of the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)
| Approved vs not approved, first review (N = 334) | Approved vs not approved, second review (n = 160) | Approved vs not approved, ever (n = 334) | ||||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Subspeciality | ||||||
| Cardiology | 1.00 (reference) | .15 | 1.00 (reference) | .0009 | 1.00 (reference) | .0001 |
| Radiology | 0.32 (0.07–1.46) | 0.38 (0.15–0.95) | 0.87 (0.44–1.72) | |||
| Neurology | 0.22 (0.03–1.70) | 0.66 (0.21–2.08) | 0.45 (0.21–0.99) | |||
| Neurosurgery | 1.10 (0.43–2.87) | 0.32 (0.11–0.91) | 0.41 (0.21–0.80) | |||
| Vascular surgery | 0.38 (0.12–1.17) | 0.12 (0.04–0.34) | 0.26 (0.14–0.47) | |||
| Percentage of asymptomatic cases | ||||||
| ≤50% | 1.00 (reference) | .85 | 1.00 (reference) | .57 | 1.00 (reference) | .67 |
| >50% | 0.93 (0.43–2.00) | 1.2 (0.64–2.25) | 1.10 (0.71–1.70) | |||
| No. of 30 day stroke complications | ||||||
| Zero | 1.00 (reference) | .23 | 1.00 (reference) | 1.00 (reference) | .69 | |
| 1 | 0.44 (0.15–1.31) | 1.11 (0.54–2.31) | .96 | 0.86 (0.51–1.43) | ||
| 2+ | 0.35 (0.05–2.67) | 1.06 (0.34–3.37) | 0.74 (0.32–1.71) | |||
| Case rate (cases/year) | 1.09 (1.06–1.13) | <.0001 | 1.002 (0.97–1.03) | .92 | 1.08 (1.05–1.11) | <.0001 |
CI, Confidence interval; OR, odds ratio.