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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: J Diabetes Complications. 2019 Oct 5;34(2):107448. doi: 10.1016/j.jdiacomp.2019.107448

Figure 1. Metabolic phenotype of mice fed a HFD.

Figure 1.

After 28 weeks, HFD-fed mice showed marked signs of obesity and T2D as evidenced by (A) Body weight (2-way ANOVA, diet effect: P<0.001), (B) Blood glucose (2-way ANOVA, diet effect: P<0.05), (C) ipGTT (t-test, P<0.001), (D) Plasma insulin (2-way ANOVA, diet effect: P<0.001), (E) HOMA-IR (2-way ANOVA, diet effect: P<0.001), and (F) Plasma total cholesterol (t test P<0.003). NFD, normal fat diet (withe); HFD, high fat diet (black); Data are mean ± SEM.