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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: J Diabetes Complications. 2019 Oct 5;34(2):107448. doi: 10.1016/j.jdiacomp.2019.107448

Figure 4. Urinary AGT, and kidney and urine Ang II levels in the HFD-induced T2D mouse model.

Figure 4.

After 28 weeks on the diet, HFD mice showed a significant elevation in (A) urinary excretion rate of uAGT (2-way ANOVA, diet effect: P<0.001; time effect: P<0.001; Sidak’s test of week 28 vs. week P<0.001). In addition, HFD increased (B) kidney Ang II levels (t-test, P=0.01) and (C) urine Ang II (t-test, P=0.02). NFD, normal fat diet (withe); HFD, high fat diet (black); Data are mean ± SEM.